About the Job :
Syngene, an internationally reputed pharmaceutical contract research organization and manufacturing body that established its journey in 1993. This company serves the purposes in the areas of medicinal chemistry, in vivo pharmacology, biology, toxicology, Process R&D, cGMP manufacturing, analytical development and custom synthesis
The firm has accreditations like iso 9001:2008. It has also animal facilities authorized by Indian authorities. Syngene serves for 331 clients globally including start-up companies. Large pharma/biotech, chemical, animal health and nutritional companies from 25 years.
The company focuses on client satisfaction areas of safety, quality, integrity and ethics. Recently it made an agreement with GSK in the area of advanced drug delivery system. Received PMDA accreditation, expanded collaboration with baxter till 2024. This has been awarded with CMO Leadership awards by life science leader magazine in Newyork.
About the Job :
Department : Oligonucleotide at Syngene Amgen R&D Centre.
Qualification: M.Sc. with 6-12 year's experience
Job of the Location: Bangalore
Job Purpose:
· Synthesis of oligonucleotides in mg scale.
· Independently handling automated oligo synthesis using solid-phase eg. OP100, Mermade, etc., and take responsibility to troubleshoot in case of challenges.
Interested candidates can share resumes to [email protected].
In-Vitro ADME- Bio analysis
Invitro ADME - Bioanalysis at #Syngene International Limited.
Qualification: M.Sc with 6 to 12 years or M.Pharm/M.Tech with 3to 9 years of relevant industrial experience
Required Experience:
· Optimization of test compounds and to develop high throughput, fit for purpose LC-MS/MS and HPLC-UV methods to support ADME samples analysis: Formulations analysis, solubility studies, stability studies, In vitro assays, MET ID and large molecule analysis etc.
· Perform analysis of samples generated for the screening of compounds for ADME assays and Processing of different matrices/formulation samples of PK studies.
· Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system.
· Hands-on experience in handling of LC-MS/MS systems is mandatory and experience on HRMS is advantageous.
· Expertise in column selection, mobile phase selection, solvent preparations and sample processing techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction.
· Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assay samples analysis.
Interested candidates can mail their CVs to [email protected]